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🩺 Ulcerative Colitis EXPLAINED: Pathogenesis, Diagnostic Criteria, Toxic Megacolon & Treatment (USMLE High-Yield Beginner’s Guide) Ever wondered how Ulcerative Colitis (UC) develops and why it can sometimes lead to toxic megacolon? In this video, we break down the pathogenesis of UC, discuss essential diagnostic criteria, and review the management strategies—including treatment options—for this chronic inflammatory bowel disease. Perfect for medical students, USMLE prep, and healthcare professionals! What You’ll Learn in This Video: ✔️ Pathogenesis: How immune dysregulation leads to chronic inflammation in the colon The role of genetic, environmental, and microbial factors in UC development ✔️ Diagnostic Criteria: Key clinical features and laboratory findings Endoscopic and histopathological criteria for UC diagnosis ✔️ Toxic Megacolon: What it is and how it complicates Ulcerative Colitis Warning signs and emergency management ✔️ Treatment Options: Medical management including aminosalicylates, corticosteroids, immunomodulators, and biologics Indications for surgical intervention ✔️ USMLE High-Yield Tips: Mnemonics and exam pearls to help you remember the critical aspects of UC ⏰ Timestamps for Easy Navigation: 0:00 Overview of Ulcerative colitis 1:20 Classification of Ulcerative colitis 2:40 Crypt abscesses 3:36 How ulcers are formed 5:00 Endoscopy criteria 5:30 Pathogenesis of clinical symptoms 7:05 Loss of Haustra (Lead pipe on X-ray) 8:29 Pseudopolyps 9:49 Risk of colorectal carcinoma 10:10 Toxic megacolon criteria and X-ray 12:34 Summary of most important features 13:10 Extraintestinal manifestations 16:47 Treatment 💬 Question for You: What do you find most challenging about diagnosing or managing Ulcerative Colitis? Share your experiences in the comments below! 😊 👍 Help Us Grow: Like this video if you found it helpful. Subscribe for more high-yield medical and USMLE content. Share this video with classmates or colleagues who need a UC refresher! ⚠️ Disclaimer: This video is intended for educational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider for personalized recommendations. https://t.me/foxterRier_med