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The Rarest Human Mutations Ranked by Probability — From 1 in 10 to 1 in 10,000,000. This video breaks down real genetic mutations and rare human traits, comparing how likely they are to occur — from left-handedness and green eyes to ultra-rare conditions like Proteus syndrome and Mirror hand syndrome. If you’ve ever wondered how rare certain human mutations actually are, this probability comparison puts the numbers into clear perspective. We start with common biological variations like left-handedness, sociopathic traits, and green eyes, then move into increasingly rare genetic conditions including heterochromia, red hair (MC1R mutation), the photic sneeze reflex, cervical ribs, hyperdontia, and polydactyly. As the probabilities shrink, the mutations become more structural and neurological — from complete color blindness (achromatopsia) and Progeria to invisible genetic anomalies like Human chimerism. Each section explains what causes the mutation, how it develops, whether it’s inherited or random, and how it affects the body or brain — all in simple, clear language. This is a deep dive into human genetics, rare disorders, probability statistics, and how small developmental changes can permanently shape anatomy, behavior, and perception. If you're interested in rare genetic mutations, human biology explained, probability comparisons, unusual medical conditions, and extreme human variations — this breakdown will completely change how you think about rarity.