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Sn2 and Sn1 reaction mechanism : Sn2 reactions are bimolecular. On the other hand, Sn1 reactions are unimolecular and have a step-wise mechanism. This process first involves bond cleavage by the LG to generate a carbocation intermediate. SN2 and SN1 reactions are types of nucleophilic substitution reaction that often involve substitution of one nucleophile (such as Br) by another nucleophile OH. SN1 reactions are nucleophilic substitutions, involving a nucleophile replacing a leaving group (just like SN2). However, SN1 reactions are unimolecular: the rate of this reaction depends only on the concentration of one reactant. SN1 reactions happen in two steps. In the SN2 reaction, the nucleophile approaches the carbon atom to which the leaving group is attached. As the nucleophile forms a bond with this carbon atom, the bond between the carbon atom and the leaving group breaks. The bond making and bond breaking actions occur simultaneously.