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Secondary amenorrhea—when someone who previously had regular periods stops menstruating for three months or more—is often a sign that something deeper is going on physiologically or hormonally 🧠💫. Here’s a comprehensive look at the most common causes: 🧬 Hormonal Imbalances Polycystic Ovary Syndrome (PCOS): Disrupts ovulation due to excess androgens and insulin resistance. Thyroid disorders: Both hypothyroidism and hyperthyroidism can interfere with menstrual cycles. Hyperprolactinemia: Elevated prolactin levels (often from a pituitary tumor) suppress ovulation. Premature ovarian insufficiency: Early menopause or diminished ovarian function before age 40. 💊 Medications & Treatments Hormonal birth control: Pills, patches, injections (like Depo-Provera) can suppress menstruation. Chemotherapy or radiation: May damage ovarian function. Antipsychotics or antidepressants: Can affect hormone levels and menstrual regularity. 🧠 Hypothalamic Causes Stress: Physical or emotional stress can suppress the hypothalamus, halting the menstrual cycle. Excessive exercise: Common in athletes or dancers with low body fat. Eating disorders: Anorexia or bulimia can lead to functional hypothalamic amenorrhea. 🏥 Structural or Anatomical Issues Uterine scarring (Asherman’s syndrome): Often from repeated D&C procedures or infections. Pelvic adhesions: Can block normal uterine function. 🧍♀️ Lifestyle & Physiologic Factors Significant weight loss or gain Chronic illnesses like diabetes or celiac disease Pregnancy and breastfeeding (though technically normal causes) #secondaryAmenorrhea