RoCK ROI and DeepRare AI Identify Elusive Molecular Signatures of Cancer скачать в хорошем качестве

RoCK ROI and DeepRare AI Identify Elusive Molecular Signatures of Cancer

Perplexity: "Single-cell RNA sequencing (scRNA-seq) reveals cellular diversity but struggles with major technical barriers, notably "zero-inflation" and incomplete transcript coverage. Standard polyA-based capture loses internal sequence alterations, limiting detection of long-range features like oncogenic splice junctions or gene fusions. The integrated RoCK–ROI workflow combines robust transcript capture with region-specific sequencing while DeepRare AI analysis recovers full-length, diagnostically relevant RNA profiles with high fidelity." https://www.nature.com/articles/s4146... https://www.nature.com/articles/s4158...