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Watch the Full Video at https://www.jove.com/v/3641/preparati.... Preparation of 3D Fibrin Scaffolds for Stem Cell Culture Applications - a 2 minute Preview of the Experimental Protocol Kathleen Kolehmainen, Stephanie M. Willerth University of Victoria , Department of Biology; University of Victoria , Department of Mechanical Engineering, Division of Medical Sciences; This work details the preparation of 3D fibrin scaffolds for culturing and differentiating plutipotent stem cells. Such scaffolds can be used to screen the effects of various biological compounds on stem cell behavior as well as modified to contain drug delivery systems. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments