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In this final part of 'Hello Nextflow', we delve into config files and their role in enabling reproducibility and portability of Nextflow pipelines. Learn how to organize, write, and structure config files to modify pipeline behavior across different environments without touching the underlying code. We explore common use cases like changing output directories and adapting pipelines to various infrastructures like HPC and cloud platforms. We also cover advanced topics such as dynamic path configurations, setting resource limits, using containers and conda for software packaging, and generating optimized configuration profiles. Join us to master the superpower of Nextflow configs! https://training.nextflow.io/latest/h... 00:00 Welcome 01:26 Config file hierarchies 02:53 0. Warmup: Run hello-config.nf 04:36 1.1. Move default values to nextflow.config 05:56 1.2. Use a run-specific configuration file 08:06 1.3. Use a parameter file 10:44 2.1. Customize the output directory with -output-dir 12:16 2.1.2. Remove hardcoded paths from the output block 13:32 2.2.1. Set outputDir in the configuration file 15:18 2.2.2. Subdirectories with batch and process names 19:33 2.3. Set the publish mode at the workflow level 21:08 3. Select a software packaging technology 25:54 4. Select an execution platform 27:07 4.1. Targeting a different backend 28:52 5. Control compute resource allocations 32:27 5.3. Set resource allocations for a specific process 33:33 5.5. Add resource limits 34:55 6. Use profiles to switch between preset configurations 37:15 6.2. Create a profile of test parameters 38:25 6.3. Use nextflow config to see the resolved configuration 39:29 Wrap up