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Watch the Full Video at https://www.jove.com/v/2306/high-reso.... High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging - a 2 minute Preview of the Experimental Protocol Mark Pierce, Dihua Yu, Rebecca Richards-Kortum Rice University, Department of Bioengineering; The Univeristy of Texas M. D. Anderson Cancer Center, Department of Molecular and Cellular Oncology; In many biological and clinical situations it is advantageous to study cellular processes as they evolve in their native microenvironment. Here we describe the assembly and use of a low-cost fiber-optic microscope which can provide real time imaging in cell culture, animal studies, and clinical patient studies. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments