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https://notonanemptymind.thinkific.com for more great, exclusive content! Register as a prospective student at my online academy free of charge or obligation to receive special notices and offers. Approved by the FDA for the treatment of Major Depression, trazodone is no longer used as monotherapy in the treatment of that condition. Instead, it is used primarily as a non-habit-forming hypnotic agent (i.e., sleeping pill) with mild antidepressant and anxiolytic (anxiety-reducing) actions. It is well-tolerated, with the most significant side effect besides sedation being dose-dependent orthostatic hypotension, requiring some care when coming to a standing position after prolonged sitting or lying flat for a while, especially first thing in the morning. It's important to remain well-hydrated and to move slowly upon standing to avoid falling or fainting. Priapism, a condition affecting between 1/8,000-1/10,000 men who take trazodone, is rare but can lead to serious complications when ignored or left untreated. Men experiencing delayed penile detumescence of greater than a few hours should immediately discontinue use of trazodone; emergency treatment involves injecting the corpus cavernosum with epinephrine, a potent vasoconstrictor.