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Скачать с ютуб ctDNA may have a prognostic role in stage III colon cancer treated with celecoxib в хорошем качестве

ctDNA may have a prognostic role in stage III colon cancer treated with celecoxib 2 дня назад


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ctDNA may have a prognostic role in stage III colon cancer treated with celecoxib

Dr Jonathan Andrew Nowak speaks to ecancer about the prognostic and predictive role of circulating tumour DNA (ctDNA) in stage III colon cancer treated with celecoxib. The study explores treatment options for colon cancer patients with lymph node involvement, emphasising the limitations of standard chemotherapy. It investigates the role of circulating tumour DNA (CT DNA) in guiding adjuvant treatment decisions. CALGB (Alliance)/SWOG 80702 trial with 2,500 patients tests FOLFOX chemotherapy with celecoxib. Findings suggest that CT DNA positivity indicates poorer survival, but celecoxib may benefit those with positive CT DNA, highlighting the need for further validation.

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