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MDS (multi-dimensional scaling) and PCoA (principal coordinate analysis) are very, very similar to PCA (principal component analysis). There really only one small difference, but that difference means you need to know what you're doing if you're going to use MDS effectively. This video make sure you learn what you need to know to use MDS and PCoA. There is a minor error at 4:14: The difference for gene 3 should be (2.2 - 1)². Instead the distance for gene 2 was repeated. For a complete index of all the StatQuest videos, check out: https://statquest.org/video-index/ If you'd like to support StatQuest, please consider... Patreon: / statquest ...or... YouTube Membership: / @statquest ...buying one of my books, a study guide, a t-shirt or hoodie, or a song from the StatQuest store... https://statquest.org/statquest-store/ ...or just donating to StatQuest! https://www.paypal.me/statquest Lastly, if you want to keep up with me as I research and create new StatQuests, follow me on twitter: / joshuastarmer #statquest #MDS #PCoA