What does a regulatory T cell (Treg) do? скачать в хорошем качестве

What does a regulatory T cell (Treg) do?

Learning objectives: Explain the anti-inflammatory cytokine producing role of the Treg cell. Describe the role of TGFβ in the Treg response and how this is a good example of a positive feedback signaling loop (common in immune responses). Explain the function of the IL-10 cytokine. Describe the cell lysis function of Treg cells. Explain how Tregs lyse other immune cells. Explain how this lysis function helps to avoid allergic and autoimmune responses. Describe how Tregs can reduce IL-2 signaling to limit immune cell proliferation. Explain the role of Tregs in preventing and causing disease.