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In the midst of rising COVID-19 case rates globally, Derek C. Angus, MD, MPH and Rochelle P. Walensky, MD, MPH return to JAMA's Q&A series to update viewers on developments in the pandemic and the critical care management of COVID-19 patients. Dr. Angus is Chief Health Care Innovation Officer at @upmc, Professor and Chair of Critical Care Medicine, and a senior JAMA editor. Dr. Walensky is Chief of Infectious Diseases at @MassGeneralHospital and a Professor at @Harvard Medical School. Recorded November 19, 2020. Topics discussed in this interview: 0:00 Introduction 0:54 US COVID-19 data update 1:26 Intubation and current standard of care 4:37 Corticosteroids 7:30 Therapies (steroids, remdesivir, tocilizumab) 10:21 Questions about remdesivir 12:30 Tocilizumab trials and press releases 17:07 Making decisions based on press releases vs clinical trials 19:18 Potential of additional therapies (cyclosporine, interferon beta, etc.) 23:44 Pre-Thanksgiving surge in cases 26:46 What is sustainable in prevention and hospital capacity 31:30 mRNA vaccines (Pfizer and Moderna) and distribution 35:11 Safety data and mRNA vaccines • Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at https://ja.ma/covidqa • Coronavirus Resource page from the JAMA Network: https://ja.ma/covidyt • To watch all the #JAMALive Q&A's Visit: https://ja.ma/covidqaytpl • Don't forget to hit subscribe or click https://ja.ma/subscribe --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • / jamajournal • / jama_current • / jamanetwork Follow the JAMA Network • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • / jamanetwork • / jamanetwork • / jamanetwork • / jamanetwork ===================================================================== #JAMALive #Coronavirus #COVID19 #SARSCoV2 #Pandemic