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This session at the 2024 ACS NCCRT Annual Meeting provided a look at the progress that 20 health systems are making to measure and tackle barriers to completion of the full continuum of colorectal cancer screening through their participation in the AMGA Foundation’s 22-month Colorectal Cancer Screening Best Practices Learning Collaborative. Moderator: Gloria Coronado, PhD, Associate Director for Population Sciences, University of Arizona Cancer Center; ACS NCCRT Vice-Chair Elect Speakers: John Kennedy, MD, President, AMGA Foundation; Chief Medical Officer, AMGA Nkem Akinsoto, MSc-PH, Assistant Director, Population Health, Primary Care & Population Health, University of Washington Physicians Network Rebecca Kaltman, MD, Executive Director and Endowed Chair, Inova Saville Cancer Screening and Prevention Center, Inova Health System Joseph J. Perez, MD, Family Medicine and Associate Medical Director Quality Assurance and Patient Safety, Lehigh Valley Health Network; Assistant Professor Family Medicine, University of South Florida Morsani College of Medicine