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The chest radiograph remains a cornerstone in thoracic imaging, offering the first diagnostic insight into a wide spectrum of pulmonary and mediastinal diseases. This educational resource systematically reviews classic radiographic signs—distinctive imaging patterns that have been established through decades of clinical observation. Key objectives include: Recognition of hallmark signs such as the air bronchogram, bat wing pattern, air crescent, Monod, water lily, bulging fissure, silhouette, and many others. Understanding mechanisms underlying these signs, including processes such as alveolar filling, lobar collapse, vascular redistribution, and air–fluid interactions. Clinical application, with emphasis on how these signs narrow differential diagnoses and guide urgent or long-term patient management. The presentation also highlights technical considerations (e.g., AP vs PA technique), pitfalls (such as artifacts, misinterpretation, and mimics), and human factors influencing diagnostic accuracy. Classic signs are contextualized with clinical cases, radiographic examples, and CT correlation, enhancing pattern recognition and reinforcing diagnostic confidence. Even as advanced modalities like CT and MRI dominate contemporary imaging, the skill of interpreting plain chest radiographs—armed with knowledge of these timeless signs—remains indispensable. Mastery of these signs continues to elevate diagnostic precision, expedite clinical decision-making, and improve patient outcomes in both emergency and routine practice. Hashtags #Radiology #ChestImaging #MedicalEducation #ClassicSigns #ThoracicRadiology #DiagnosticRadiology #Radiographics #RSNA #Residents #PulmonaryImaging © 2025 AI Chavelle™ by Jeffrey Chen / SmartRad AI. All rights reserved.