John Gásdal Karstensen – Video Comment on “Confocal laser endomicroscopy: a novel method for ...” скачать в хорошем качестве

John Gásdal Karstensen – Video Comment on “Confocal laser endomicroscopy: a novel method for ...”

Confocal laser endomicroscopy: a novel method for prediction of relapse in Crohn’s disease John Gásdal Karstensen, Adrian Săftoiu, Jørn Brynskov, Jakob Hendel, Pia Klausen, Tatiana Cârtână, Tobias Wirenfeldt Klausen, Lene Buhl Riis, Peter Vilmann In a single-center, prospective study, Karstensen et al. evaluated the potential utility of confocal laser endomicroscopy for Crohn’s disease. They found that ileal and colorectal fluorescein leakage, ileal microerosions, and colonic vascular alterations were significantly more frequent in patients with endoscopically active Crohn’s disease than in those with inactive Crohn’s disease or in control patients. Interestingly, during a 12-month follow-up period, ileal fluorescein leakage and microerosions were significant risk factors for relapse. They concluded that confocal laser endomicroscopy can identify reproducible microscopic changes in the terminal ileum that are risk factors for relapse in patients with otherwise inactive Crohn’s disease. Bibliography DOI http://dx.doi.org/ 10.1055/s-0034-1393314 Published online: 19.11.2015 Endoscopy 2016; 48: 364–372 © Georg Thieme Verlag KG Stuttgart · New York ISSN 0013-726X