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Donate to PCRI: https://pcri.org/donate/ For more information, visit https://pcri.org 0:29 At what point does PSA rise start to indicate potential cancer? 1:30 What should a PSA nadir be, approximately following radiation? 4:12 Does a downward trend in PSA mean treatment is working? 5:21 How sharp is a PSA "bump" usually, in term of points? 6:28 Following a nadir, at what point does another rise become a red flag? 8:41 What if a patient never reaches that PSA nadir? 9:20 Do different kinds of radiation cause different rates of PSA decline? 10:09 What does a PSA nadir look like following hormone therapy? 11:06 What counts as a significant PSA rise following hormone therapy? 12:15 What kind of PSA growth might indicate resistance? 13:44 What is PSA doubling time, and what does it indicate? 15:49 Is PSA useful for monitoring patients on active surveillance? 19:25 Alex's conclusions Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org To learn more about prostate cancer, visit http://www.pcri.org Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: https://pcri.org/join Who we are: The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.