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New research suggests fasting & autophagy support the regeneration integrity of the gut barrier. Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: https://bit.ly/berberine-fasting-acce... Use code podcast at checkout to save Link to show notes and research: https://bit.ly/2RCnAI2 ----------------------------------------Show Notes------------------------------------- 0:00 Intro 2:05 The best way to enhance autophagy is with diet and exercise. 2:44 mTOR is the autophagy break and AMPK is the gas. AMPK also puts the break on mTOR. 3:25 These enzymes cannot be directly tested. 4:20 If your glucose is high in a fasted morning test, you may not be experiencing autophagy. 4:40 Your body upregulates APT with activity after your night’s fast. This increases AMPK and puts the breaks on mTOR. 5:40 mTOR is activated in the post meal window. This helps you body take the nutrients. 7:00 Exercise stimulates AMPK, as does intermittent fasting and taking berberine hydrochloride. 7:40 Paneth cells are key at releasing antimicrobial peptides which keep pathogens from entering. 9:40 Endotoxin/LPS (lipopolysaccharides) are found on the surface of gram-negative bacteria. Because of these, many of us with leaky gut have low grade sepsis after every meal. 10:44 Paneth cells and intestinal stem cells are intimately connected to the autophagy process. 12:20 Paneth cells control your intestinal stem cells. Stem cells help replenish and repair damaged cells. 14:00 Intestinal permeability can be tested via Dunwoody Labs. 14:22 Tight junction proteins are the mortar for your gut lining. 15:50 Dysfunction in your gut endothelium cross-talks with lung and cardiovascular endothelium.