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How reliable is the science behind evolution? In this episode, we dive into a critical examination of evolutionary theory with insights from Dr. Rob Stadler, a biomedical engineer, and Dr. James Tour, a synthetic organic chemist. We explore: Why microevolution is high-confidence science, while macroevolution and abiogenesis remain speculative. The six criteria for evaluating scientific claims, including repeatability, direct measurement, and minimizing bias. Key challenges to traditional evidence: the fossil record, genetic similarity, and orphan genes. Chemical and biological hurdles to the origin of life and major body-plan changes. Lessons from long-term evolution experiments that highlight the limits of random mutations and natural selection. Discover why these scientists advocate for a “Forest of Life” model instead of the traditional Tree of Life, and why intellectual humility is essential when teaching evolution. If you’re curious about the boundaries of science and the unanswered questions in evolution, this video is for you.