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Date of event: January 21,2026 Speaker: -Jeff Plomley Scientific Director, Altasciences -Mingluan Chen Principal Research Scientist, Altasciences -Neil Spooner Director Spooner Bioanalytical Solutions & Chair Patient Centric Sampling Interest Group Intended audience: -Scientists developing and validating methods for small and large molecules extracted from dried blood microsamples -Clinical researchers and key decision makers involved with microsampling device selection -Biotech and Pharma groups leveraging microsampling to facilitate drug development -Investigators exploring the patient-centric approach to sample collection -Microsampling manufacturers interested in real world applications and device performance What you will learn: -A bioanalytical-driven strategy for microsample device selection -Extraction techniques to overcome HCT-induced recovery bias and age-related extractability -Approaches for stabilization of labile analytes via substrate pre-treatment -Workflows for extraction and analysis of antisense oligonucleotides from dried blood microsamples -Evaluations required for validation of microsampling assays in the regulated space Chapters: 00:00 -- Introduction to the webinar and speakers, overview of microsampling devices, and key challenges. 02:40 -- Volumetric Microsampling Technologies 09:45 –Bioanalytical Challenges & Extraction Strategies 22:00 – Capitainer B Device & Anti-Tuberculosis Case Study 40:00 -- ASO Bioanalysis: Challenges & LC-MS Workflows 52:02–ASO Method Optimization, Robustness & Wrap-Up