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Watch the Full Video at https://www.jove.com/v/55383/a-protoc.... A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment - a 2 minute Preview of the Experimental Protocol Bradley Endres, Eugénie Bassères, Tasnuva Rashid, Long Chang, M. Jahangir Alam, Kevin W Garey University of Houston College of Pharmacy, Department of Pharmacy Practice and Translational Research; University of Houston, Department of Electrical and Computer Engineering; Antibiotic efficacy is most commonly determined by conducting killing kinetic studies and measuring colony forming units (CFUs). By integrating scanning electron microscopy (SEM) with these standard methods, we can distinguish the pharmacological effects of treatment between different antibiotics. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments