How does the CliniMACS Prodigy® perform magnetic cell separation? скачать в хорошем качестве

How does the CliniMACS Prodigy® perform magnetic cell separation?

Watch this animation to learn more about this principle of column-based magnetic cell separation. For more information visit https://www.miltenyibiotec.com/produc... Cell separation of magnetically labeled cells takes place in the MACS® Column, a component of the CliniMACS Prodigy® Tubing Set. The column contains a matrix composed of superparamagnetic spheres, which are covered with a cell-friendly coating. When the column is placed in the CliniMACS Prodigy Magnet Unit , the spheres amplify the magnetic field 10,000-fold. This induces a strong magnetic field within the column that retains cells being labeled with nano-sized MACS MicroBeads or CliniMACS Reagents. Inside the magnetic column, the space between the spheres is about 20 times the size of a lymphocyte, so cells can move freely and are only retained by magnetic forces. This ensures a gentle flow of cells, without pressure, sticking or compression, allowing cell integrity and characteristics to be preserved. Cells are then fully functional ready for downstream applications. Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. Our innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Our technologies cover techniques of sample preparation, cell isolation, cell sorting, flow cytometry, cell culture, molecular analysis, and preclinical imaging. Our 30 years of expertise spans research areas including immunology, stem cell biology, neuroscience, and cancer, and clinical research areas like hematology, graft engineering, and apheresis. In our commitment to the scientific community, we also offer comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has 2,500 employees in 28 countries – all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.