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This video is the opening of the Heavy Ion Therapy Master Class Online School. The Master Class was held from May, 17 to May 21, 2021. It focuses on Heavy Ion Therapy Treatment Planning Systems (TPS) and includes lectures, treatment planning tool demonstrations, hands-on exercises and student projects. It is based on the professional, open-source, research toolkit matRad, tailored to students’ and researchers’ requirements and proven to provide efficient means for training on TPS methods. The masterclass is targeted primarily towards students and early-stage researchers who show strong promise and interest in becoming part of the heavy ion research community and who may then exploit and access Europe's heavy ion therapy research infrastructures. ___________ This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101008548