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Sources - hair.queen.holli on TT PMID 24600476 A skin biopsy is considered one of the most definitive and reliable methods of diagnosis for many skin conditions, including cancers, infections, and inflammatory diseases. During a biopsy, a small sample of skin tissue is removed and examined under a microscope by a pathologist, allowing doctors to directly observe the cellular structure and pattern of disease. This level of microscopic detail provides a high degree of diagnostic accuracy that cannot usually be achieved through visual examination alone. However, while skin biopsies are highly accurate, they are not completely infallible. Rare errors can occur due to factors such as sampling the wrong area, early or subtle disease changes, or interpretive differences between specialists. Despite these uncommon limitations, a skin biopsy remains the gold standard for confirming a diagnosis, guiding treatment decisions, and ensuring patients receive the most appropriate care. #medicine #diagnosis #skin