Leveraging High- and Medium-Throughput Automation for Process Development at Merck / MSD скачать в хорошем качестве

Leveraging High- and Medium-Throughput Automation for Process Development at Merck / MSD

This webinar was proudly sponsored by Technobis and organised by ScientificUpdate - a leader in expert-led trainings, conferences, and webinars in organic chemistry. Guest speaker: Madeleine Deem, Senior Scientist, Data Rich Experimentation at Merck Webinar topic: Laboratory automation enables faster and more efficient data generation while minimizing material consumption. This presentation demonstrates how Merck’s Data Rich Experimentation group applies automated platforms to collect time course reaction profiles across different stages of drug development. Three case studies were presented which illustrate the versatility of our automation suite: 1. Early Process Development: A custom Tecan Evo workflow was developed to profile monoclonal antibody (mAb) reduction kinetics, enabling detailed characterization during initial process design. 2. Route Scouting: The ReactALL provided enhanced reaction insights that guided optimization decisions when evaluating synthetic routes. 3. Tech Transfer: The ReactALL was deployed to de-risk a key impurity during technology transfer. These examples demonstrate how tailored automation solutions can be strategically applied throughout the drug development lifecycle to generate high-quality time course data efficiently.