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Please see CYSTADROPS full Prescribing Information and Important Safety Information. Important Safety Information: https://bit.ly/3Fuu8fb Full Prescribing Information and Instructions for Use: https://bit.ly/3zdwMnj INDICATION(S) AND IMPORTANT SAFETY INFORMATION WHAT is CYSTADROPS? CYSTADROPS (cysteamine ophthalmic solution) 0.37% is a prescription medicine used to treat corneal cystine crystal deposits in the eye in adults and children with cystinosis. IMPORTANT SAFETY INFORMATION Before starting CYSTADROPS, tell your healthcare provider (HCP) about all your medical conditions, including if you are pregnant or plan to become pregnant, breastfeeding or plan to breastfeed. Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements. To minimize the risk of contamination, do not touch the dropper tip to the eyelids, surrounding areas, or to any surface. Keep bottle tightly closed when not in use. What are the possible side effects of CYSTADROPS? CYSTADROPS may cause serious side effects including: •A condition where the pressure inside the skull increases for unknown reasons has been reported with cysteamine taken by mouth or cysteamine eye drops (used at the same time as cysteamine taken by mouth). This condition went away with the addition of medicine that increases the production of urine. •Use with soft contact lenses should be avoided as CYSTADROPS contains the preservative benzalkonium chloride which may be absorbed by soft contact lenses. Remove contact lenses prior to application. Lenses may be reinserted 15 minutes following administration. The most common side effects of CYSTADROPS are eye pain (stinging), blurred vision, eye irritation (burning), eye redness, discomfort at instillation site (sticky eyes or sticky eyelids), eye itching, watery eyes, medicine deposit on the eye lashes or around the eyes. These are not all the possible side effects of CYSTADROPS. Call your HCP for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088 or visit www.fda.gov/medwatch. CYSTADROPS® (cysteamine ophthalmic solution), for topical ophthalmic use, is available as 3.8 mg/mL of cysteamine (0.37%) in 5 mL bottles. Please see the accompanying full Prescribing Information. Cystadrops is a licensed trademark of Recordati Rare Diseases Inc. Other trademarks, registered or otherwise, are the property of their respective owner(s). © 2025 Recordati Rare Diseases Inc.