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complement pathway Animation - Classial Pathway , Alternative pathway , Lectin pathway

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash complement pathway - Classical Pathway, Alternative pathway, Lectin pathway - General Pathology The complement system or complement pathway includes a Group of proteins that circulate in the blood as inactive precursors. After stimulation by antibody complexes or by pathogens, complement proteases can activate other complement precursors, leading to a cascade of reactions that is referred to as “complement activation.” The complement system can enhance the function of antibodies and phagocytes as discussed in this animated video. Activation ---------------- Classical pathway: activated by IgM or IgG complexes binding to the pathogen (via C1) Alternative pathway: activated directly by pathogen rather than by antigen-antibody complexes (via C3) Lectin pathway (via C1-like complex) Effect --------- Opsonization: the process of altering bacteria to increase their susceptibility to phagocytosis. C3b and IgG are the two main opsonins for bacteria (via C3b). Lysis of bacteria (particularly gram‑negative bacteria). C5–C9 form the membrane attack complex (MAC) → perforation of the cell wall → cell lysis Activation of mast cells and granulocytes (C3/C4/C5) → anaphylaxis Chemotaxis of neutrophils → C5a Clearance of immune-complexes → C3b Inhibition --------------- DAF decay-accelerating factor (CD55) C1 esterase inhibitor → e.g. on red blood cells #complementpathway #classicalcomplementpathway #alternativecomplementpathway #lectinpathway #complementpathwayanimation #complementpathwayvideo #complementpathwaypathology

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