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In today's video, we are comparing 2 older second-generation antipsychotics, olanzapine, and risperidone. Time stamps of each topic covered are listed below: Intro 00:00 How do olanzapine and risperidone work? 00:23 What are olanzapine and risperidone used for? 03:27 Side effects of olanzapine and risperidone 04:53 Considerations of taking olanzapine and risperidone 07:36 Black box warning 07:50 Monitor Labs 08:25 Neuroleptic Malignant Syndrome 10:31 Extra Pyramidal Symptoms 11:03 Orthostatic Hypotension 12:39 Seizures 13:20 Final thoughts 14:02 🙋🏽♀️ Join this channel to access exclusive LIVES, priority comments/questions answered, and more!: / @levelheadedmind 📚 Useful Resources: Deprescribing Guide: : https://amzn.to/4dZEUMk Drug Interaction Checker-https://www.drugs.com/drug_interactio... Brain Food Report- https://www.levelheadedmind.com/brain... Neurotransmitter Questionnaire- https://www.levelheadedmind.com/neuro... 🎥 This video was edited by: Rahul Kanchi / rahulkanchi24 🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor. You can find a list of international crisis lines here: https://blog.opencounseling.com/suici... References: Alsherbiny MA, Li CG. Medicinal Cannabis-Potential Drug Interactions. Medicines (Basel). 2018 Dec 23;6(1):3. doi: 10.3390/medicines6010003. PMID: 30583596; PMCID: PMC6473892. He, S., Yu, W. J., Wang, X., Zhang, L., Zhao, N., Li, G., Shen, Y. F., & Li, H. (2020). Risk factors of hyperprolactinemia induced by risperidone and olanzapine and their correlations with plasma glucose and lipids. General psychiatry, 33(4), e100206. https://doi.org/10.1136/gpsych-2020-1... Olanzapine FDA Label (2009). Retrieved from https://www.accessdata.fda.gov/drugsa... Risperdal FDA Label (2009). Retrieved from https://www.accessdata.fda.gov/drugsa... Shoja Shafti, S., & Gilanipoor, M. (2014). A Comparative Study between Olanzapine and Risperidone in the Management of Schizophrenia. Schizophrenia research and treatment, 2014, 307202. https://doi.org/10.1155/2014/307202 Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press. Stahl, S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press. Uptodate (2022). Olanzapine: Drug Information. Retrieved from https://www-uptodate-com.libproxy.eku... UptoDate (2022). Risperidone: Drug information. Retrieved from https://www-uptodate-com.libproxy.eku... Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.