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In this deep-dive session, Dr Shouptik Basu, Surgical Oncology faculty at DigiNerve, explores the evolution of laryngeal cancer treatment from the era of open surgeries to modern-day organ preservation protocols. What You Will Learn: Understanding the evidence behind Induction Chemotherapy is crucial for both clinical practice and Superspeciality entrance exams. This video breaks down the complex landscape of landmark clinical trials that shifted the paradigm toward saving the patient’s "voice." Key Highlights: The Concept of Organ Preservation: How the revolution of the 1980s changed the treatment approach for Stage 3 and Stage 4 laryngeal cancers. Landmark Trials Simplified: Veterans Laryngeal Trial: Survival outcomes and the 64% preservation rate. EORTC Trial: Focus on hypopharyngeal involvement and long-term outcomes. RTOG 91-11: Sequential vs. Concurrent CTRT. GORTEC & TAX 323/324: TPF vs. PF regimes and the role of induction chemotherapy. Clinical Decision Making: When is a larynx considered "dysfunctional" and why does it necessitate upfront surgery? Post-Treatment Evaluation: Timelines for clinical assessment (6-8 weeks) vs. PET-CT (12 weeks) and the role of rehabilitation. Salvage Laryngectomy: Indications and success rates following failed chemoradiation. Faculty Dr Shouptik Basu Consultant Surgical Oncologist MBBS (Hons, Gold Medalist), MS (Gold Medalist), DNB (Gold Medalist), MCh(AIIMS), MRCS(Edin.), MRCS(Glasg.), MNAMS, FMAS, FSSO, FAIS, Fellowship (Robotic Surg). About Surgery SS (Version2.0): Surgery SS (Version 2) has a holistic approach, equipping students with essential clinical skills and lecture-based knowledge tailored for exam preparation, NEET SS and INI SS, including residency in broad and Superspeciality. The course encompasses all major super specialties, such as Surgical Oncology, GI and HBP Surgery, Neurosurgery, Urology, Plastic Surgery, CTVS & Pediatric Surgery, offering a well-structured and comprehensive learning experience. About DigiNerve: DigiNerve is an EdTech initiative by Jaypee Brothers, a pioneer and market leader in health science publishing with a legacy spanning over five decades. It aims to provide high-quality content to build strong concepts, acquire clinical skills, and excel in exams under the guidance of top faculty members. DigiNerve extensively covers the entire MBBS syllabus with the latest updates and helps students prepare for medical entrance exams, such as: ✅ NEET PG Entrance Exam ✅ National Exit Exam (NEXT) for MBBS ✅ DNB Exit Exam DigiNerve introduces a new dimension to MBBS preparation, providing structured NEET PG coaching and postgraduate courses to enhance learning and success in medical education. ✅ Superspeciality entrance examinations and Residency NEET SS, INI SS, MCh and DrNB #LaryngealCancer #SurgicalOncology #OrganPreservation #NEETSS #INISS #MedicalEducation #DigiNerve #DrShouptikBasu #OncologyTrials #HeadAndNeckCancer