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Peter F. Orio III, DO, MS, discusses radiation oncology for localized prostate cancer. He focuses on a range of advanced techniques aimed at delivering high-dose radiation to the tumor while minimizing toxicity to surrounding tissues. Key modalities include Image-Guided Radiation Therapy (IGRT), Intensity-Modulated Radiation Therapy (IMRT), Stereotactic Body Radiation Therapy (SBRT), and adaptive radiation therapy, each providing distinct advantages in precision and dose management. Dr. Orio discusses emerging technologies like MR-guided linear accelerators (MR-Linacs), and controversial options like proton therapy and prostate brachytherapy. He also addresses evolving advanced radiation techniques, with artificial intelligence growing in treatment planning and execution. Despite these advances, ongoing research is necessary to validate the clinical benefits of these technologies and ensure they effectively reduce toxicity and improve patient outcomes. The overarching goal remains to provide personalized, precision radiation therapy that maximizes tumor control while minimizing harm to patients. Don't forget to join the GRU Community: https://grandroundsinurology.com/regi... Follow us on Twitter/X: https://x.com/GRUrology And like and subscribe to us here on YouTube!