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Mickey Shaposhnik, CEO of Next Plus, reveals why traditional MES is dead and how AI-powered manufacturing execution is helping factories capture tribal knowledge, eliminate paper-based processes, and deploy electronic batch records in weeks instead of years. Giveaway to Industry40tv listeners 1-Year Free Access to Next Plus: https://nextplus.io/industry40-tv-giv... 𝗣𝗼𝗱𝗰𝗮𝘀𝘁 𝗹𝗶𝗻𝗸𝘀: • Spotify: https://open.spotify.com/episode/3f14... • Apple: https://podcasts.apple.com/de/podcast... 𝗧𝗶𝗺𝗲𝘀𝘁𝗮𝗺𝗽𝘀: 0:00 - Introduction: AI-Powered Manufacturing Execution 2:51 - Why Paper-Based Manufacturing Is Failing in 2025 5:07 - Data Collection Challenges on the Shop Floor 6:02 - The "Garbage In, Garbage Out" Problem with Digital Forms 8:23 - AI Voice-to-Form: Eliminating Data Entry Friction 9:37 - Bridging the Knowledge Gap Between Business and Shop Floor 13:19 - Why "Training" Is Dead in Manufacturing 15:03 - Building Your Factory's Internal YouTube & Wikipedia 16:28 - The Four Pillars of AI-Driven Manufacturing Execution 17:09 - Digital Work Instructions, Data Collection, Analytics & SOP Creation 20:27 - Why the MES Monolith Is Broken 21:46 - Low Volume, High Mix: Why Agility Beats Rigidity 23:56 - How AI Learns and Generates Insights on the Shop Floor 24:30 - Fault Reports & AI Agents: 20-50% Reduction in Expert Calls 28:54 - Humanoid Robots Still Need Tribal Knowledge 29:49 - IT/OT Integration: MQTT, OPC UA & Open Architecture 30:34 - Three Cybersecurity Architectures for MES Deployment 33:24 - Scaling Globally: How AI Eliminates the $100K Translation Problem 38:02 - Real-World Use Cases: Aerospace to Pharma 38:28 - Electronic Batch Records (EBR): From 2 Years to 6 Weeks 40:49 - 2015 Mindset vs. 2025 Technology Capabilities 41:22 - The COVID Vaccine Lesson: Speed of AI Transformation 42:24 - Skip Pilots, Start Small Projects: Advice for Manufacturing Leaders 43:24 - Where to Find Miki Shaposhnik AI in Manufacturing Podcast with Kudzai Manditereza ********************* Connect With Me: • LinkedIn: / kudzaimanditereza • Website: https://www.industry40.tv/ ******************** Guest - Mickey Shaposhnik ******************* • Website: https://nextplus.io/ • Mickey on LinkedIn - / sakranolog ******************* PODCAST SPONSORED BY HiveMQ: https://www.hivemq.com/