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This video delves into the lung illnesses which may be caused by the use of vapes. Specifically, it explores the risk of using illicit vape cartridges and how they may lead to pulmonary issues. Subscribe to the McMaster Demystifying Medicine YouTube channel: / demystifyingmedicine This video is provided for general and educational information only. Please consult your health care provider for Information about your health. This video was made by McMaster students Nazlim Bilgi, Pirouz Emami, Irzam Gondal, & Seyed Amirhossein Pishva in collaboration with the McMaster Demystifying Medicine Program. We tank Dr. Martin Kolb for help with the project. Copyright McMaster University 2019. References: Butt, Y. M., Smith, M. L., Tazelaar, H. D., Vaszar, L. T., Swanson, K. L., Cecchini, M. J., ... Larsen, B. T. (2019). Pathology of vaping-associated lung injury. New England Journal of Medicine. doi:10.1056/nejmc1913069 Carlos, W. G., Crotty Alexander, L. E., Gross, J. E., Dela Cruz, C. S., Keller, J. M., Pasnick, S., & Jamil, S. (2019). Vaping associated pulmonary illness (VAPI). American Journal of Respiratory and Critical Care Medicine. doi:10.1164/rccm.2007p13 Henry, T. S., Kanne, J. P., & Kligerman, S. J. (2019). Imaging of vaping-associated lung disease. New England Journal of Medicine, 381(15), 1486–1487. doi: 10.1056/nejmc1911995 Hswen, Y., & Brownstein, J. S. (2019). Real-time digital surveillance of vaping-induced pulmonary disease. New England Journal of Medicine, 381(18), 1778–1780. doi: 10.1056/nejmc1912818 Layden, J. E., Ghinai, I., Pray, I., Kimball, A., Layer, M., Tenforde, M., ... Meiman, J. (2019). Pulmonary illness related to e-cigarette use in illinois and wisconsin — preliminary report. New England Journal of Medicine. doi: 10.1056/nejmoa1911614 Lerner, C. A., Sundar, I. K., Yao, H., Gerloff, J., Ossip, D. J., McIntosh, S., ... Rahman, I. (2015). Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung. PLOS ONE, 10(2), e0116732. doi:10.1371/journal.pone.0116732 Maddock, S. D., Cirulis, M. M., Callahan, S. J., Keenan, L. M., Pirozzi, C. S., Raman, S. M., & Aberegg, S. K. (2019). Pulmonary lipid-laden macrophages and vaping. New England Journal of Medicine, 381(15), 1488–1489. doi: 10.1056/nejmc1912038 Miech, R., Johnston, L., O’Malley, P. M., Bachman, J. G., & Patrick, M. E. (2019). Trends in adolescent vaping, 2017–2019. New England Journal of Medicine, 381(15), 1490–1491. doi: 10.1056/nejmc1910739 Schier, J.G., Meiman, J.G., Layden, J., et al. (2019). Severe pulmonary disease associated with electronic-cigarette–product use — interim guidance. MMWR Morb Mortal Wkly Rep 2019;68:787–790. doi: 10.15585/mmwr.mm6836e2