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Most women enter perimenopause with little guidance and even less support. What if stabilizing hormones starts with strengthening the gut, preserving muscle, and rebuilding foundational health before symptoms escalate. In this episode of Extend, we sit down with Dr. Amy Shah, double board certified physician in internal medicine and immunology, to unpack the powerful link between the gut microbiome, estrogen metabolism, and women’s longevity. We explore the estrobolome, why 30 grams of fiber and 30 grams of morning protein create metabolic stability, how training smarter protects bone and brain health, and when hormone therapy becomes appropriate. We break down practical strategies to build physiological reserve, from early DEXA scans and ferritin testing to sprint intervals, strength training, fermented foods, and personalized hormone decisions that prioritize long term outcomes. ✅ We Also Discuss: ➡️ Why perimenopause remains underserved in medicine ➡️ The estrobolome and estrogen metabolism ➡️ Pre, pro, and postbiotics for gut resilience ➡️ 30 grams of fiber and morning protein ➡️ Strength training and sprint work in midlife ➡️ Cortisol overload and recovery ➡️ Ferritin, vitamin D, and overlooked lab markers ➡️ Early DEXA scans and body composition tracking ➡️ The three clear indications for hormone therapy ➡️ Women’s cardiovascular differences and small vessel disease Subscribe for science driven conversations on longevity, metabolic health, hormone optimization, and building a future defined by strength, vitality, and agency over your own biology. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: / darshanshahmd Learn more about Dr. Amy Shah: Website: https://amymdwellness.com/ IG: / dramyshah TikTok: / dramyshah Youtube: / @dramyshah LinkedIn: / amyshahmd Podcast: https://amymdwellness.com/pages/podcast Hashtags: #HormonalHealth #Perimenopause #Menopause #GutHealth #Estrobolome #WomensLongevity #MuscleAndBone #StrengthTraining #DEXAScan #Ferritin #PreventiveMedicine #Healthspan #Longevity #HealthOptimization #DrDarshanShah #AmyShah #ExtendPodcast