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This video describes two key challenges associated with treating liver and pancreatic tumors: immunosuppression and high intratumoral pressure. Together, these barriers can limit the efficacy and delivery of immunotherapy drugs, resulting in poor clinical outcomes. To overcome these challenges, TriSalus Life Sciences has engineered the Pressure-Enabled Drug Delivery™ (PEDD™) approach with SmartValve™ technology, which has been shown to overcome high intratumoral pressure and improve therapy delivery during outpatient interventional radiology procedures. By integrating this technology with an investigational immunotherapy, SD-101, TriSalus’ treatment platform has the potential to enable durable responses to immunotherapeutic agents in liver and pancreatic tumors. While meaningful progress in these difficult-to-treat diseases will not be easy, TriSalus is focused on advancing science and technological innovation to transform outcomes for patients. To learn more, visit www.trisaluslifesci.com.