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In this episode, Dr. Arasi Maran and Dr. Rana Pullatt discuss medical treatments for obesity, focusing on interventions to break the dopamine pleasure cycle and food addiction aspect of obesity. They explore the history of obesity medicine and the challenges in developing effective medications. They discuss various medications used for obesity treatment, including hormonal therapies, seizure control medications, and GLP-1 agonists. They emphasize the importance of a multidisciplinary approach to obesity treatment, involving psychologists, dietitians, and other specialists. They also discuss the role of thyroid dysfunction and other factors in obesity. Takeaways: Developing effective medications for obesity has been challenging, with many failures in the past.There are various medications used for obesity treatment, including hormonal therapies, seizure control medications, and GLP-1 agonists. A multidisciplinary approach involving psychologists, dietitians, and other specialists is crucial for successful obesity treatment. Thyroid dysfunction and other factors can contribute to obesity and should be considered in treatment. Titles Exploring Medical Treatments for Obesity Different Medications for Obesity Treatment Sound Bites "What are the interventions we can do to break the dopamine pleasure cycle and the food addiction aspect of obesity." "Developing medications for obesity has been a huge challenge." "Fentamine is just not good enough isolated and shouldn't be used for weight loss purposes." Chapters 00:00 Introduction and the Pleasure Cycle of Obesity 01:15 Challenges in Developing Effective Medications 07:52 GLP-1 Agonists and Weight Loss Mechanisms 11:44 The Importance of a Multidisciplinary Approach #medicaltreatments #obesity #interventions #dopaminepleasurecycle #food addiction, history, medications, hormonal therapies, seizure control medications, GLP-1 agonists, multidisciplinary approach, thyroid dysfunction