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If water seems to be making your kiddo's skin go haywire, one big culprit is low levels of filaggrin, a protein that's basically a superhero of the skin. It keeps the skin barrier in check, preventing it from getting leaky, and also helps the skin make its own natural moisturizing factors. The FLG gene makes this protein, but sometimes, mutations in it can lead to low filaggrin levels. But hold on, it's not just genetics wreaking havoc. Inflammation and environmental factors like irritating substances, low humidity, chilly weather, and pollution can also cause low filaggrin. So, even if your kiddo doesn't have the FLG gene mutation, they might still be dealing with low filaggrin levels, especially if they have eczema or psoriasis. Now, here's how low filaggrin can mess with your child's skin: 👉 It increases the skin's pH, making it more alkaline, and that's not good for healthy skin because skin pH needs to be acidic. 👉 It's a big contributor to itchy skin. 👉 It leads to leaky skin, which opens the door for more allergens to sneak in through the weakened skin barrier, paving the way for IgE allergies (food and environmental). 👉 It invites unfriendly bacteria to set up camp on the skin, like Staph aureus. 👉 It leaves your kid's skin dry, and lacking hydration and the skin's natural lipids that keep it healthy. Unfortunately, there's no magic test for the FLG mutation or filaggrin levels (at least not as of the timing of my writing this), but if your kiddo's skin has that alligator or elephant look, has a history of Staph infections on their skin, or is irritated by water, low filaggrin might be the culprit. You can do something about it! Filaggrin needs histidine to do its job, and lucky for us, that's an amino acid made by gut bacteria. In babies, they can't produce it yet, so it needs to come from their diet. Turns out, histidine-rich foods can be the hero your kiddo's skin needs. Think meat, dairy, legumes, fish, nuts, seeds, eggs, and whole grains. And there you have it – the lowdown on filaggrin, histidine, and how to show your kiddo's skin some love. 🌟 #bacteria #gutbacteria #microbiome #jennifercarynbrand #filaggrin https://www.learnskin.com/courses/nat...