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TransFuse (Transformative Fusion of Innovative Blood Management Technologies) 2011 will be held April 14--15 at the JW Marriott Desert Ridge Resort in Phoenix. This multidisciplinary conference is focused on optimizing blood transfusion for patients by exploring state-of-the-art science and technology. This meeting is co-sponsored by leaders in blood management from both Mayo Clinic and Cleveland Clinic. Conference highlights will include an active learning classroom and a free iPad application for Blood Management decision making for all attendees. The application is a decision-aid tool designed as a game allowing users to win points by making the best clinical transfusion decisions. Users will also learn about world-class transfusion practices and participate in the development of clinical consensus. See for yourself the first glimpses of this new iPad app as Mayo Clinic's Mark H. Ereth, M.D. offers some in-depth details.