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Bladder Perimeter Measurements for Improved Overactive Bladder Phenotyping: An Ultrasound Repeatability Study in Healthy Controls Li R1, Maddra K2, Nagle A1, Vinod N2, Prince S1, Tensen S3, Naimi H2, Sheen D2, Kolli H2, Carucci L4, Klausner A2, Speich J1 1. Department of Mechanical & Nuclear Engineering, Virginia Commonwealth University, RIchmond, VA, 2. Department of Surgery/Division of Urology, Virginia Commonwealth University, RIchmond, VA, 3. Department of Biomedical Engineering, Virginia Commonwealth University, RIchmond, VA, 4. Department of Radiology, Virginia Commonwealth University, RIchmond, VA KEYWORDS: Imaging, Anatomy, Overactive Bladder The potential value of non-invasive ultrasound (US) imaging for the analysis of overactive bladder (OAB) has been highlighted in recent studies that have quantified bladder shape and its association with OAB [1, 2]. In these studies, bladder shape parameters have been determined by manual tracing of bladder perimeters in US images. Gray et al., developed a method to estimate bladder sphericity using 2D US images during filling and found that deviations from sphericity correlated with non-voiding bladder contractions [2]. Glass Clark et al., found that bladder height-to-width ratios in 5/11 women with OAB were outside 95% confidence intervals derived from a group of age and body mass index-matched women without OAB [1]. For bladder shape diagnostics for OAB to be clinically relevant, the measures must be sufficiently repeatable. Therefore, the objective of the present study was to assess the repeatability of bladder shape parameters from ultrasound images obtained from multiple fills and during multiple clinic visits. Read the full abstract text here: https://www.ics.org/2020/abstract/322