Caseation Necrosis / Caseous Necrosis ; Definition, Characteristics and Examples of Diseases with Ca скачать в хорошем качестве

Caseation Necrosis / Caseous Necrosis ; Definition, Characteristics and Examples of Diseases with Ca

Caseation necrosis is a type of necrosis that occurs in response to infection, typically with Mycobacterium tuberculosis. It is characterized by: 1. Cheesy or caseous appearance of the affected tissue 2. Softening and liquefaction of the tissue 3. Formation of a granuloma, a cluster of immune cells attempting to contain the infection 4. Central necrosis, with dead cells and debris accumulating in the center of the granuloma 5. Fibrosis, with scar tissue forming around the granuloma Caseation necrosis is often seen in: 1. Tuberculosis (TB) - pulmonary, extrapulmonary, or disseminated 2. Leprosy 3. Fungal infections (e.g., histoplasmosis, cryptococcosis) 4. Syphilis The combination of necrosis, inflammation, and attempted repair leads to the characteristic caseous appearance. Caseation necrosis is a hallmark of TB and helps diagnose the disease. #CaseationNecrosis