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TRT, SHBG & Health – Facts, Questions and Evolution - https://themenshealthclinic.co.uk/trt... Should you try and manipulate your SHBG or manipulate factors that contribute to your SHBG level? Anabolic processes predominate at rest, so sleep is an incredibly important part of that process. Approximately 60% of your testosterone is bound to SHBG, 38% weakly bound to albumin and 2% is free. Have you ever wondered why only 2% of your total testosterone level is free? It’s because the primary role of testosterone is growth and repair, free T is relatively unimportant. SHBG helps mediate the transfer of testosterone within the cell to perform its function. It’s only when catabolic processes predominate through the action of cortisol do you have a slight increase in free T. You need testosterone and energy for biosynthesis, creating complex and specialised compounds from simple molecules. What have we done since the invention of the light bulb? We’ve become sicker. We’ve interfered with Mother Nature, we’ve significantly reduced the time available for these essential processes to occur. We forget we are animals. Is there any other species that is as sick as ours?!