Biodegradable Flow Diverters for Cerebral Aneurysms w/ Dr. Alim Mitha | BackTable Ep. 406 скачать в хорошем качестве

Biodegradable Flow Diverters for Cerebral Aneurysms w/ Dr. Alim Mitha | BackTable Ep. 406

In this episode of the Back Table Innovation Podcast, host Dr. Diana Velazquez-Pimentel, a radiologist and biomedical engineer, chats with Dr. Alim Mitha about the novel idea of biodegradable flow diverters and the future of interventional neuroradiology. Dr. Mitha is a cerebrovascular, endovascular, and skull base neurosurgeon and biomedical engineer at the University of Calgary. During his neurosurgery residency, Dr. Mitha also completed a master’s degree in biomedical engineering. Afterwards, he pursued additional fellowships in cerebrovascular and skull base surgery, as well as endovascular neurosurgery. Since then, he has started a research lab focused on tissue engineering and biomedical device development. He explains the role of flow diverters and how they are used to guide blood flow away from the intracranial aneurysms. While flow diverters have been applied to treatment of many different types of aneurysms, Dr. Mitha notes that these devices carry thrombogenic risks. During his training, he saw that it was not preferable to deploy a flow diverter in a young patient who would have to remain on antiplatelet therapy for the rest of their life. As a result, Dr. Mitha began to develop a polymer-based biodegradable flow diverter that could be absorbed by the body after the aneurysm had been occluded, in addition to being visible on non-invasive imaging. He explains the process of building a prototype, incorporating a company, joining a start-up incubator, and now performing first in-human-clinical trials. --- CHECK OUT OUR SPONSOR RADPAD® Radiation Protection https://www.radpad.com/ --- SHOW NOTES 00:00 - Introduction 03:12 - Understanding the Role of Flow Diverters 08:24 - The Conception of a Biodegradable Flow Diverter 11:42 - The Challenges and Successes in Prototyping 14:00 - A Path Towards Commercialization 16:17 - Considerations for Clinical Adoption 24:07 - Developing Skills for Engineering and Entrepreneurship 27:36 - First-In-Human Trials and Early Feedback 30:43 - Innovating Within the University of Calgary --- RESOURCES University of Calgary Creative Destruction Lab: https://creativedestructionlab.com/lo... The Brain Conferences: https://www.fens.org/meetings/the-bra... --- The BackTable Podcast is a resource for interventional radiologists, vascular surgeons, interventional cardiologists, and other interventional and endovascular specialists to learn tips, techniques, and the ins and outs of the devices in their cabinets. Get notified when new episodes drop! Subscribe to the BackTable Podcast on your go-to podcast platform, and follow us on your social media platform of choice for regular vascular and interventional updates. ► https://www.backtable.com/shows/vi/su...