3. Sympathoplegics: Introduction: Anti- Hypertensive Drugs: CVS Pharmacology скачать в хорошем качестве

3. Sympathoplegics: Introduction: Anti- Hypertensive Drugs: CVS Pharmacology

📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash 3. Sympathoplegics: Introduction: CVS Pharmacology --------------------------------------------------------------------------------------- Sympathoplegics are a class of drugs that inhibit the sympathetic nervous system (SNS) 🧠⚡, reducing heart rate ❤️, cardiac output 💓, and vascular resistance 🩸 to manage cardiovascular conditions like hypertension (HTN) 🩺, angina 💢, and heart failure. These drugs work by blocking adrenergic receptors (alpha & beta), reducing norepinephrine (NE) release, or suppressing central SNS activity, leading to vasodilation 🏞️, lowered blood pressure, and decreased myocardial oxygen demand. 🔹 Centrally Acting Sympathoplegics (Alpha-2 Agonists) 🧠 – Drugs like Clonidine & Methyldopa activate α2 receptors in the brain, reducing sympathetic outflow. Methyldopa is preferred in pregnancy-induced hypertension 🤰🩸, while clonidine is also used for withdrawal symptoms 🚬. Side effects include sedation 😴, dry mouth, and rebound hypertension. 🔹 Ganglion Blockers (e.g., Hexamethonium, Trimethaphan) 🚧 – Block autonomic ganglia, once used for severe hypertension, but now obsolete due to widespread side effects. 🔹 Adrenergic Neuron Blockers (e.g., Reserpine, Guanethidine) 🛑 – Deplete norepinephrine (NE) stores, leading to reduced vasoconstriction but causing severe depression 🥀, sedation, and GI issues. 🔹 Alpha-Blockers (e.g., Prazosin, Doxazosin) 🚦 – Selective α1-blockers cause vasodilation, reducing blood pressure & improving urinary flow in BPH (benign prostatic hyperplasia) 🚽. Side effects include first-dose hypotension and reflex tachycardia. 🔹 Beta-Blockers (e.g., Metoprolol, Propranolol, Carvedilol) 💓 – Block β1 & β2 receptors, reducing heart rate, BP, and myocardial oxygen demand, widely used in hypertension, angina, CHF, and arrhythmias. Sympathoplegics are powerful antihypertensives, but careful monitoring is essential to avoid hypotension, bradycardia, and CNS side effects. 🌿✨ #Sympathoplegics 💊 #CVSPharmacology 🩺 #BloodPressureControl 🩸 #BetaBlockers 💓 #AlphaBlockers 🚦 #HypertensionTreatment #HeartHealth ❤️ #MedicalEducation 📚 #MBBSNotes #StudySmart 🧠 #NeuroPharmacology 🧬 #SafeCardiacTherapy #CNSDrugs ⚡ #medicalanimations #fmge #fmgevideos #rapidrevisionfmge #fmge2024 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2025 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #usmlestep2videos