NEOPLASIA-1: BASICS: Nomenclature: Benign, Malignant, Mixed tumors, teratoma,Hamartoma, choristoma скачать в хорошем качестве

NEOPLASIA-1: BASICS: Nomenclature: Benign, Malignant, Mixed tumors, teratoma,Hamartoma, choristoma

In this short tutorial i have described the the basic concepts of neoplasia, which includes the understanding various nomenclatures in neoplasia.. Visit http://ilovepathology.com/ for more topics in Pathology! ***Follow me**** Twitter :   / vijaypatho     / ilovepathology2   Facebook:   / ilovepathology   Tumor"--literally any swelling. First described by Celsus Hippocrates: Greek physician Father of medicine Noticed,that the blood vessels surrounding the malignant tumor like the claws of crab. He first coined the word “Karkinos” ( Greek for Crab) Carcinos or Carcinoma in English! Claudius Galen: Greek Physician Second century AD used the word oncos (Greek for swelling) to describe tumors.  distinguished tumors that are: “According to nature"--pregnant uterus “Exceeding Nature"--pus “Contrary to nature"--what we now know as neoplasms /New growth Neoplasia: “new growth” Tumour: a swelling DEFINITION: “ RUPERT ALLAN WILLIS” Neoplasm- Abnormal mass of tissue Growth Exceeds and is uncoordinated with that of normal tissue Persists after cessation of causative stimuli IN THE PRESENT ERA IT CAN BE Defined as Disorder of cell growthTriggered by a series of acquired mutations of a single cell And its clonal progeny MIXED TUMORS Single neoplastic cell can differentiate into different types of cells Eg: Pleomorphic adenoma of the salivary gland The epithelial components are admixed with myxoid stroma But both are derived from a single clone which is capable of producing both cell types TERATOMA These tumors contain mature or immature cells which are derived from more than one germ cell layer Sometimes all three! Greek ( teras) - monster these tumors originate from totipotential germ cells. Ovary, testis,embroyonic rests HAMARTOMA Benign masses Disorganized, but contain cells indigenous to the involved site ( composed of the elements which are normally found at that site. Hamartomas in the lung/heart etc.. CHORISTOMA Heterotopic rest of cells. Excess of normal tissue in abnormal location!!! Eg: Pancreatic tissue as a small mass, can be seen in the stomach or small intestine