什么是肺纤维化 高鹏 徐州矿务集团总医院 скачать в хорошем качестве

什么是肺纤维化 高鹏 徐州矿务集团总医院

什么是肺纤维化 高鹏 徐州矿务集团总医院 肺纤维化是以成纤维细胞增殖及大量细胞外基质聚集并伴炎症损伤、组织结构破坏为特征的一大类肺疾病的终末期改变，也就是正常的肺泡组织被损坏后，经过异常修复导致结构异常（疤痕形成）。绝大部分肺纤维化病人病因不明，这被称为特发性间质性肺炎。而特发性间质性肺炎中以肺纤维化病变为主要表现形式的疾病类型为特发性肺纤维化，是一种能导致肺功能进行性丧失的严重的间质性肺疾病。肺纤维化严重影响人体呼吸功能，表现为干咳、进行性呼吸困难（自觉气不够用），且随着病情和肺部损伤的加重，患者呼吸功能不断恶化。 What is pulmonary fibrosis Pulmonary fibrosis is a kind of end-stage changes of lung diseases characterized by fibroblast proliferation, a large number of extracellular matrix aggregation, inflammatory damage and tissue structure destruction, After normal alveolar tissue is damaged, Abnormal repair leads to structural abnormality (scar formation). Most patients with pulmonary fibrosis have unknown etiology, This is called idiopathic interstitial pneumonia. In the idiopathic interstitial pneumonia, the disease type with pulmonary fibrosis as the main manifestation is idiopathic pulmonary fibrosis, It is a serious interstitial lung disease that can cause progressive loss of lung function. Pulmonary fibrosis seriously affects human respiratory function, The symptoms are dry cough, progressive dyspnea (insufficient conscious Qi), And with the aggravation of disease and lung injury, The respiratory function of the patients was deteriorating.