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An explanation of the distinction between the pharmacological phrases affinity and efficacy. Drugs with affinity to receptor bind to it - drugs with efficacy to a receptor evoke a response upon binding. A drug with affinity but no efficacy, is an antagonist; a drug with both affinity and efficacy is an agonist. Related videos: Agonists vs Antagonists - • Agonists & Antagonists Specificity vs Selectivity - • Specificity vs Selectivity | Revision vid... Subscribe to DrugsPlus: / @drugsplus Knock your GCSE, A level or university exam results out of the park with DrugsPlus. With videos on physiology, disease and drugs, this is your number one stop for anything involving medical health. Topics covered range from the heart, to the brain; from the reproductive system, to the endocrine system; from cyanide, to COVID-19. People who enjoy DrugsPlus include everyone from prospective medical students, to anyone with a general interest in drugs and disease. DrugsPlus solely exists for educational purposes and should not be used for personal medical advice, nor as an aid to self-diagnosis – always consult with your physician or healthcare professional.