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Parturition & Lactation

Parturition and Lactation Physiology with Dr. Faiza Understand how labor starts, progresses, and completes. See how lactation begins and sustains. Clear, system-linked physiology for MBBS and PG learners. 🔬 Key Topics Covered: Stages of Labor: Cervical dilation, delivery of baby, delivery of placenta. Typical timelines and what drives each stage. Positive Feedback Loop: Stretch → oxytocin → stronger contractions → more stretch. Hormonal Triggers: Rising estrogen/progesterone ratio, oxytocin surge, prostaglandins from decidua, fetal pituitary and adrenal signals (CRH → ACTH → cortisol; DHEA-S → placental estrogen). Placental Clock and Inflammation: Surfactant proteins, uterine stretch, and cytokines that help initiate labor. Hemostasis and Puerperium: Myometrial contraction clamps vessels; uterine involution timelines (faster with breastfeeding). Breast Development: Estrogen (ducts, fat), progesterone and hPL (lobulo-alveolar growth). Milk Production vs Ejection: Prolactin makes milk; oxytocin ejects milk. Suckling reflex pathways and role of dopamine withdrawal. Colostrum and Human Milk: Early high-protein, Ig-rich colostrum; human vs cow milk differences. Lactational Amenorrhea: Prolactin suppresses GnRH/LH/FSH, delaying cycles. Breastfeeding Benefits: Passive immunity, gut flora support, maternal uterine involution. 🎓 Learning Objectives: Explain the endocrine cascade that initiates labor. Describe the three stages of labor and their regulation. Differentiate milk production and ejection mechanisms. Outline the composition and benefits of colostrum and human milk. Relate prolactin’s role to lactational amenorrhea. 💡 Clinical Relevance: Use labor physiology to time interventions safely. Support active management of the third stage to prevent PPH. Counsel on early and exclusive breastfeeding. Recognize when lactation support or endocrine evaluation is needed. 📚 Learning Resources (copy and paste as plain text): Phone: +92 310 7990649 Email: [email protected] Website: https://www.medicoseacademics.com/ Facebook:   / medicoseacademics   Instagram:   / medicoseacademics   YouTube:    / @medicoseacademics   Dr. Muhammad Ali Rabbani Assistant Professor MBBS, FCPS MHPE Fellow Surgical Research (Fellowship) LinkedIn:   / yourprofile   Tags: Parturition, Labor Physiology, Stages of Labor, Oxytocin, Prostaglandins, Estrogen Progesterone Ratio, Placental Clock, Fetal Cortisol, CRH ACTH Axis, Cervical Dilation, Uterine Involution, Postpartum Hemostasis, Lactation, Prolactin, Milk Ejection Reflex, Colostrum, Human Milk vs Cow Milk, Lactational Amenorrhea, Breastfeeding Benefits, Obstetrics Physiology