Pharmaceutics/Lecture-10/CONTAINERS AND CLOSURES/MATERIALS USED FOR CONTAINERS/Pharmacy Technician скачать в хорошем качестве

Pharmaceutics/Lecture-10/CONTAINERS AND CLOSURES/MATERIALS USED FOR CONTAINERS/Pharmacy Technician

Welcome to PharmaLecture – Your Trusted Source for Quality Pharmacy Education CONTAINERS AND CLOSURES Packaging: it is the art and science in preparing a product for transport, storage, display and use. Pharmaceuticals are suitably packed so that they should retain their therapeutic effectiveness from the time of their packaging till they are consumed. A package may consist of: Container: In which the drug is placed and is in direct contact with the drug. Closure: This seals the container to exclude oxygen, carbon dioxide, moisture, microorganisms and prevent the loss of volatile substances. It also prevents the loss of medicament during transport and handling. TYPES OF CONTAINERS According to method of closure and use 1. Well closed containers To protect the preparation from contamination and to prevent the loss of potency of active constituents during transport, storage and handling. 2. Air-tight containers To protect preparation from atmospheric contamination of liquids, solids or vapours. Prevent loss of drug due to efflorescence or evaporation. 3. Light resistant containers Protect drugs which undergo decomposition in the presence of light. These drugs may be enclosed in amber colored or opaque containers. 4. Hermetically sealed containers Which does not allow the air and other gases to pass through it. Generally used for injectable. A glass ampoule sealed by fusion is most common example. 5. Single dose containers They are used to supply only one dose of the medicament. e.g ampoules 6. Multi-dose containers This type of container hold a number of doses. It is sealed in such a way that successive doses can be withdrawn easily. e.g.multidose vials 7. Aerosol containers Containers for aerosol must be strong enough to withstand the pressure evolved at the time of use of the preparation. 8. Temper-Evident Container These are closed containers fitted with a device that irreversibly indicates if the container has been opened. According to their shapes 1.Glass / polyethylene bottles a) Narrow mouth Liquid oral preparations intended to be swallowed like syrups, elixirs, emulsions, suspensions are required to be dispensed in narrow mouthed bottles. b) Wide mouth Semi-solid preparations like ointments, creams, pastes are dispensed in wide mouth containers. On manufacturing scale collapsible tubes are preferred. 2.Dropper bottles Eye drops, Ear drops, Nasal drops should be dispensed in amber colored glass bottles fitted with a dropper. 3.Collapsible tubes 4.Ampoules 5.Vials 6.Polythene packets for intravenous fluids 7.Envelops, strips, blister packs, cartons, boxes. Solid dosage forms like tablets, hard and soft capsules are generally packed in strips. Individual powders are dispensed in paperboards or plastic boxes MATERIALS USED FOR CONTAINERS 1. Glass 2. Plastics 3. Metals 4. Paper They are used either singly or sometimes in combination with each other. TYPES OF CLOSURES Closures are available in five basic designs: 1. Screw-on These are of two types a) Threaded screw cap When screw cap is applied its threads engage with the corresponding threads moulded on the neck of bottles. b) Lug cap It is similar to threaded screw cap and operates on same principle but it has interrupted thread on closure instead of a continuous thread .it is widely used in food industry. i.e. jam bottle caps. 2. Crimp-on These are crown type closures used as crimped closures for beverage bottles and remain unchanged for more than fifty years. 3. Press-on a) Snap seals : these are used in Cac 1000 b) Bung seals: they are conical and can be inserted for about half their length into the neck of container. Rubber is excellent material for bung closure i.e. closure of vials of penicillin powders 4. Roll-on The aluminum roll on cap can be sealed securely, opened easily and resealed effectively. Pilferproof types of roll on closures are available for glass and plastic bottles. These are thread less straight For any question Whats app +923038489485 Email jspharma116@gmail.com Subscribe now and equip yourself with the knowledge and confidence to succeed in the dynamic field of pharmacy.