Orthobiologics: Hype vs. Reality with Dr. Scott Rodeo скачать в хорошем качестве

Orthobiologics: Hype vs. Reality with Dr. Scott Rodeo

In this episode, Dr. Scott Rodeo, a leading orthopedic surgeon, explains the enormous potential of regenerative medicine in orthopedics. The episode explores how orthobiologics offer new hope for millions suffering from musculoskeletal diseases and pain, while also providing a clear-eyed view of the field’s challenges. Dr. Rodeo highlights innovative practices in orthopedic research, particularly focusing on stem cell therapy and its uses in osteoarthritis management. He discusses how these advancements could revolutionize treatments by targeting symptoms and examines whether they may be able to go further and modify cell structures in the future. Note: This lecture was recorded in March 2023. Learn more about Dr. Scott Rodeo’s work: https://www.hss.edu/physicians_rodeo-... Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-davi... Time stamps: 00:00:17: Intro 00:02:14: Dr. Scott Rodeo 00:03:05: The potential and limitations of regenerative medicine 00:06:08: Understanding stem cells 00:12:25: Mesenchymal STROMAL (MSC) cells and connective tissue progenitors 00:14:20: The availability and limitations of stem cells for clinical use 00:18:00: How might exogenous cells work? 00:20:24: Regulatory constraints on cell sorting and expansion 00:23:14: Why biologics can be symptom-modifying but are not likely to be structure-modifying 00:24:27: Biologic targets in treatment and tailoring therapy to the underlying pathology 00:26:55: The role of cell therapy in treating osteoarthritis 00:28:03: Inflammation in osteoarthritis and cell therapy 00:30:35: Role of cells in modifying local inflammatory environment 00:34:49: MSCs as a strategy to target macrophages in osteoarthritis 00:36:15: Research shows cells can have a positive effect on knee osteoarthritis 00:42:00: Are stem cells structure-modifying? Research shows significant potential 00:46:56: Studies show non-cultured cells show promise too 00:48:24: The potential and future approaches of cell therapy — About: Atria’s Vanguard Symposia is a lecture series where some of the world’s most compelling researchers translate leading-edge science into medicine. In each episode, top experts share breakthrough science about preventive health care, dive deep into headline-grabbing topics, and take you beyond the buzzwords to explain the latest in longevity science. Our show will arm you with practical information and the tools of discernment to cut through the hype and understand what matters most. Atria Health and Research Institute aims to accelerate a global shift from reactive sick care to proactive, preventive health care. We work at the forefront of science and technology and we believe a collaborative approach to modern medicine can extend healthy life for all. Learn more: https://www.atria.org/ Subscribe to Atria’s Vanguard Symposia on: Apple Podcasts: https://bit.ly/AtriaVanguardApplePodc... Spotify: https://bit.ly/AtriaVanguardSpotify Sign up for our newsletter: https://bit.ly/Atria-Newsletter The information contained in this podcast is for general informational and educational purposes only and does not constitute or serve as a substitute for professional medical advice, treatment, or diagnosis. Always consult the advice of your personal health care provider when seeking medical advice for any condition you may have, and never delay treatment or disregard advice from a professional health care provider based on something you have seen or heard in this content. No part of this podcast can be reproduced, redistributed, published, copied or duplicated in any form without the prior written permission of Atria.