CNT to study Pharmacodynamic Effects on CNS by Cholinergic Drugs | Protocol Preview скачать в хорошем качестве

CNT to study Pharmacodynamic Effects on CNS by Cholinergic Drugs | Protocol Preview

Watch the Full Video at https://www.jove.com/v/56569/a-comput.... A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development - a 2 minute Preview of the Experimental Protocol Ellen P. Hart, Ricardo Alvarez-Jimenez, Esther Davidse, Robert Jan Doll, Adam F. Cohen, Joop M.A. Van Gerven, Geert Jan Groeneveld Centre for Human Drug Research (CHDR), Leiden,; A validated computerized battery of neuropsychological and neurophysiological tests is used to study pharmacodynamic effects on the central nervous system of newly developed drugs in early phase development. To demonstrate the test battery, the acute effects of mecamylamine and the reversal of these effects by two agonist drugs are described. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments