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In this comprehensive lecture, we review core dermatologic pharmacology concepts essential for Physician Assistant students and clinical trainees. The focus is on practical prescribing, patient counseling, and clinical decision-making—not memorization alone. 🔍 Topics covered include: Acne pathophysiology and treatment targets Topical and oral retinoids (mechanism, uses, counseling, safety) Topical antivirals for HSV (acyclovir, penciclovir, docosanol) Anti-infestation therapies for scabies and lice (permethrin, ivermectin, malathion, spinosad) Step-by-step patient education for scabies and head lice treatment Common cutaneous adverse drug reactions Exanthematous drug eruptions Urticaria and angioedema Vaccine site reactions Red flags for severe reactions (SJS/TEN) Topicals 101: where to apply, how much (FTU), how often, and duration Counseling pearls to improve adherence and safety Safe dermatologic prescribing: what to document and why Clinical decision-making framework: pathogen, location, severity, patient factors, and access 💡 This lecture emphasizes high-yield clinical pearls, common mistakes to avoid, and how proper counseling prevents treatment failure and unnecessary adverse effects. 🎯 Ideal for: PA students NP and medical students Primary care and urgent care clinicians Anyone looking to strengthen their dermatology fundamentals 👍 If you found this helpful, don’t forget to like, subscribe, and share with your classmates!